期刊論文 Publications
期刊論文 Publications
Pei, J.C., Luo, D.Z., Gau, S.S., Chang, C.Y., Lai, W.S., Directly and Indirectly Targeting the Glycine Modulatory Site to Modulate NMDA Receptor Function to Address Unmet Medical Needs of Patients With Schizophrenia. Front Psychiatry, 12:742058, 2021.
Chang, C.Y.*, Luo, D.Z.*, Pei, J.C.*, Kuo, M.C., Hsieh, Y.C., Lai, W.S., Not Just a Bystander: The Emerging Role of Astrocytes and Research Tools in Studying Cognitive Dysfunctions in Schizophrenia. Int J Mol Sci., 22(10),5343, 2021. (*These authors contributed equally to this work)
Pei, J.C., Hung, W.L., Lin, B.X., Shih, M.H., Lu, L.Y., Luo, D.Z., Tai, H. C., Vincent Studer, Min, M. Y., Lai, W.S., Therapeutic potential and underlying mechanism of sarcosine (N-methylglycine) in N-methyl-D-aspartate (NMDA) receptor hypofunction models of schizophrenia. Journal of Psychopharmacology, 33:1288-1302, 2019.
Pan, M.K., Kuo, S.H., Tai, W.C., Pei, J.C., Wang, Y.M., Liu, C.H., Lai, W.S., Kuo, C.C., Neuronal codes outweigh circuitry oscillations in parkinsonian motor control. The Journal of Clinical Investigation, 126:4516–26, 2016.
Huang C.M., Hong, T.W., Wang Y.J., Chen K.C., Pei, J.C., Chuang T.Y., Lai W.S., Tsai S.H., Chu Richard, Chen W.C., Sheen L.Y., Takahashi Satoru, Ding S.T., Shen T.L., Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse model. BMC Complementary and Alternative Medicine, 16:310, 2016
Pei, J.C., Liu, C.M. & Lai, W.S. Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficits. Frontier E-Book 2015.
Huang, C.H., Pei, J.C., Luo, D.Z., Chen, C., Chen, Y.W., Lai, W.S., Investigation of gene effects and epistatic interactions between Akt1 and neuregulin 1 in the regulation of behavioral phenotypes and social functions in genetic mouse models of schizophrenia. Frontiers in Behavioral Neuroscience, 8:455, 2015
Pan, M.K., Tai, C.H., Liu, W.C., Pei, J.C., Lai, W.S., Kuo, C.C., Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficits. The Journal of Clinical Investigation, 124: 4629-41, 2014
Pei, J.C., Liu, C.M. & Lai, W.S. Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficits. Frontier in Behavior Neuroscience, 8:126, 2014.
Lai, W.S., Chang, C.Y.*, Wong, W.R.*, Pei, J.C.*, Chen, Y.S., Hong, W.L. Assessing schizophrenia-relevant cognitive and social deficits in mice: a selection of mouse behavioral tasks and potential therapeutic compounds. Current Pharmaceutical Design, 20:5139-50, 2014. (*These authors contributed equally to this work)
Juan, L.W., Liao, C.C., Lai, W.S., Chang, C.Y., Pei, J.C., Wong, W.R., Liu, C.M., Hwu, H.G., and Lee, L.J. Phenotypic characterization of C57BL/6J mice carrying the Disc1 gene from the 129S6/SvEv strain. Brain Structure and Function, 219:1417- 31, 2013.